Founded in 1975 as an independent research institution, now part of Vilnius University, the Institute of Biotechnology strives to maintain the high standards of excellence in scientific endeavour, research training and technological advance with its main focus in a broadly defined field of molecular biotechnology including nucleic acid and protein technologies, bioinformatics, molecular diagnostics, drug design, next generation epigenomic and gene editing technologies. The Institute provides an interface between advanced education, basic research and technological development for the economic and social benefit of Lithuania.

 

Current Grants

Spausdinti

FRAMEWORK 7 PROGRAMME

Towards construction of a comprehensive map of amyloid-ligand interactions:
(-)-Epigallocatechin 3-Gallate and insulin amyloid (EGCG+INSULIN=). 2011-2015. Dr. V. Smirnovas.

Integrated Microfluidic System for Long Term Cell Cultivation, Monitoring and Analysis. BioCellChip, 2012-2015. Dr. L. Mažutis.

NATIONAL INSTITUTE OF HEALTH

Direct single nucleotide mapping of genomic CpG marks. 2013-2015. Prof. S. Klimašauskas.

PROJECTS OF THE EUROPEAN SOCIAL FUND UNDER GLOBAL GRANT MEASURE

Molecular tools for epigenomics and RNomics. 2011-2015. Prof. Habil. Dr. S. Klimašauskas.

Structure and molecular mechanisms of bacterial antivirus defence systems. 2011-2015. Prof. Dr. V. Šikšnys.

Novel chimeric proteins with antiviral activity. 2012-2015. Dr. A. Žvirblienė.

Design of selective carbonic anhydrase, Hsp90, and Hsp70 inhibitors and investigation of their anticancer properties. 2012-2015. Dr. D. Matulis.

The use of genome-wide analysis for engineering of new yeast strains with improved heterologous expression. 2012-2015. Dr. R. Slibinskas.

Exploring flavones as universal inhibitors of amyloid-like fibril formation.  2012-2015. Dr. V. Smirnovas.

Making use of large-scale biological data for the development of a new method to assess protein models and for studying DNA replication and repair systems in bacteria and viruses. 2013-2015. Dr. Č. Venclovas.


RESEARCH COUNCIL OF LITHUANIA


Development of new diagnostic tools for hepatitis E virus infection and studies of HEV prevalence in Lithuania. 2015-2018. dr. Indrė Kučinskaitė-Kodzė.

Single molecule and structural studies of a new type of restriction endonucleases. 2015-2018. dr. Mindaugas Zaremba.

Identification and analysis of small non-coding RNAs of gram positive lactic acids bacteria involved in resistance to antibiotics. 2015-2018. dr. Giedrius Vilkaitis.

Signalling components in stem cells. 2014-2016. dr. A.Schweighofer.

Protein ligand binding volume and its application in drug design. 2014-2016. dr. V.Petrauskas.

The role of Cas1 ir Cas2 proteins in adaptation mechanism of CRISPR-Cas systems. 2014-2016.  dr. G.Gasiūnas.

Bayesian nonparametrics for detection of distant protein homology. 2013-2015. dr. M. Margelevičius.

Genomic mapping of covalently tagged CpG sites. 2013-2015. dr. E. Kriukienė.

Synthesis of Schmallenberg virus proteins and their application for diagnostic means. 2013-2015. prof. K. Sasnauskas

Investigation of RNA interference in bacteria. 2013-2015. dr. G. Tamulaitis.

Structural and functional studies of restriction enzyme family. 2013-2015. dr. G. Tamulaitienė.

Expansion of the Crystallography Open Database (COD) and Statistical Analysis of Crystal Structures. 2013-2015. dr. S. Gražulis

Expression analysis of anthocyanin biosynthesis genes in horticultural plants. 2012-2015. Dr. V. Kazanavičiūtė

SWISS-LT

Directed evolution of computer designed enzymes using droplet  based microfluidics. 2012-2016. prof. A.Janulaitis

Signalling control  of pathogen induced plant immunity. 2013-2016. dr. I.Meškienė.

NATIONAL COMPLEX PROGRAMME

Biotechnology and Biopharmacy: fundamental and applied research. 2012-2015. prof. K.Sasnauskas.

JOINT RESEARCH PROGRAMME

Development of new generation means for virus diagnostics and prophylaxis and application in veterinary medicine. 2013-2015. dr. A.Gedvilaitė