Biotechnologijos institutas yra mokslinių tyrimų institucija, siekianti užtikrinti valstybės pažangą sparčiai besivystančiose gyvybės mokslų ir biotechnologijų srityse, plėtoti tarptautinio lygio molekulinės biotechnologijos tyrimus, skatinti tarpdisciplininius tyrimus bei mokslo ir verslo bendradarbiavimą
Grants developed till 2010
FRAMEWORK 7 PROGRAMME
Small molecule inhibitors of the trimeric influenza virus polymerase complex (FLUINHIBIT). 2008-2010. dr. G.Žvirblis
FRAMEWORK 6 PROGRAMME
Meganucleases for gene replacement. 2006-2008. prof. dr. V.Šikšnys
Inhibition of Cancer by Disrupting Interaction Between Polo-like Kinase 1 Polo-box Domain and Spindle Targets. 2006-2008. dr. J.Matulienė
A multidisciplinary approach to the study of DNA enzymes down to the single molecule level. 2005-2009. prof. dr. V.Šikšnys
Targeting newly discovered oxygen sensing cascades for novel cancer treatments, biology equipment, drugs. 2004-2008. dr. A.Kanopka
Molecular modeling-based characterization of protein complexes involved in DNA repair. 2004-2006. dr. Č.Venclovas
Drug design by structural thermodynamics. 2004-2006. dr. D.Matulis
ScanBalt Competence Region – a model case to enhance European competitiveness in life sciences, genomics and biotechnology for health on a global scale. 2004-2006. habil. dr. A.Pauliukonis
Rational design and comparative evaluation of novel genetic vaccines. 2004-2008. prof. K.Sasnauskas
FRAMEWORK 5 PROGRAMME
Support for the integration of “newly associated states” in the European research area “Biotechnology Centre of Excellence of Lithuania”. 2003-2006
Development of highly special enzymes for genome manipulation. prof. 2003-2004. dr. V.Šikšnys
Enhanced Laboratory Surveillance of Measles. 2002-2005. prof. K.Sasnauskas
Combined immune and gene therapy for chronic hepatitis. 2001-2003. prof. K.Sasnauskas
Comprehensive risk analysis of dioxins: development of methodology to assess genetic susceptibility to developmental disturbances and cancer. 2000-2003. dr. A.Kanopkas
Bivalent hantavirus vaccine for Europe: Different approaches and evaluation in animal models. 1999-2003. prof. K.Sasnauskas
FRAMEWORK 4 PROGRAMME
Molecular monitoring and pathological role of HCV, HGV and altered HBV genomes in the Baltic countries. 1998-2001. prof. K.Sasnauskas
Detection, identification and typing of the Mycobacterium tuberculosis in the Baltic countries. 1998-2003. dr. P. Stakėnas
Recombinant viral particulate proteins as tools for new vaccines and diagnostics. 1994-1997. prof. K.Sasnauskas
HOWARD HUGHES MEDICAL INSTITUTE
Structural characterization of protein interactions in DNA replication, repair and recombination processes through molecular modelling. 2006-2010. dr. Č. Venclovas
Towards engineering of restriction enzymes. 2003-2004. prof. dr. V. Šikšnys
Bioinformatics-guided engineering of DNA methyltransferases. 2003-2004. dr. Č. Venclovas
Sequence recognition and base flipping by DNA methyltransferases: Structural studies and redesign for novel functions. 2001-2005. prof. S.Klimašauskas
Principles of restriction enzymes specificity. 2001-2005. prof. dr. V.Šikšnys
Combination of improved methods with expert knowledge to derive models of protein structure at low sequence homology. 2001-2005. dr. Č.Venclovas
Mechanisms of specific protein-DNA recognition and modification. 1996-2000. prof. S.Klimašauskas
NATIONAL INSTITUTE OF HEALTH
Methylome profiling via DNA Methyltransferase directed labelling. 2008-2010. prof. S. Klimašauskas
WELLCOME TRUST
Cross-talk between functional domains of BfiI restriction endonuclease. 2005-2006. prof. dr. V. Šikšnys
Restriction enzymes with novel restriction mechanisms. 2001-2003. prof. dr. V.Šikšnys
Calorimetric Studies of DNA- Restriction Enzyme Interactions. 1999-2001. prof. dr. V.Šikšnys
STRUCTURAL FUNDS
Building of Infrastructure for Proteomics Research. 2007-2008
Improving Skills of Researchers in Proteomics. 2007-2008
Establishment of Post Doc Internship in Natural Sciences. 2006-2008
Gaining Practical Skills in Biotechnology during Postgraduate Studies. 2006-2008
Improving Skills of Researchers in Material Science, Biotechnology and Environmental Investigations. 2006-2007
Improving Quality of Human Resources in Research and Innovation. 2006-2007
Agricultural and Forest Biotechnology Research Network. 2005-2006
Improving Quality of Human Resources in Agricultural Biotechnology and Forestry Investigations. 2005-2006
Training of Postgraduates and Ph. D. Students in Agricultural and Forest Biotechnology. 2005-2006
Strengthening of Experimental Basis for Interdisciplinary Research in Material Science, Biotechnology and Environmental Investigations. 2005-2006
Developing Skills and Competence of Researchers and Experts in Genomics for Cardiology. 2005-2006
Introducing to scientific community investigations on stem cells and cells of higher differentiation. 2005-2006
EUROPEAN ECONOMIC AREA
Anticancer drug design by structural biothermodynamics. 2008-2010. dr. D.Matulisx
NATIONAL GRANTS
High-Technology Development programme
Development of new tools for improved laboratory diagnosis of human papillomavirus (HPV) infection and HPV-related cancer. 2009-2010. dr. A.Žvirblienė
Development of Yeast expression system by using proteomic approach and gene engineering. 2008-2010. prof. K.Sasnauskas
New enzymes and technologies for epigenome analysis. 2007-2009. prof. S.Klimašauskas
Structural and functional studies of T4 phage replisome. 2007-2009. prof. dr. V.Šikšnys
Generation of new monoclonal antibodies directed to desired epitopes using chimeric virus-like particles. 2005-2006. dr. A.Žvirblienė
New molecular tools for biotechnology. 2003-2006. prof. V.Šikšnys
Enhanced surveillance of respiratory viruses. 2003-2006. prof. K.Sasnauskas
Industrial Biotechnology Programme
Development of diagnostic tools for Merkel cell polyoma virus. 2009-2010. dr. R.Slibinskas
Development of anti-cytolysin monoclonal antibodies designed to neutralize the toxic cytolysins of the pathogenic bacteria. 2008-2010. r. E. Mištinienė
Search for novel biofuel components and technological investigations to produce second generation biofuel. 2007-2009. dr. B. Surinėnaitė
Design of technologies of recombinant proteins for prolonged therapy. 2007-2009. dr. G.Žvirblis
Use of biotechnological methods for carbonic anhydrase inhibitors search. 2007-2009. dr. D.Matulis
Engagement of metagenomic analysis of extremophile viruses from hot underground waters of Lithuania searching for the new enzymes. 2007-2009. r. A.Gedvilaitė
Detection of phytoplasmas and viroids in plants valuable for industrial biotechnology and their removal. 2007-2009. dr. R. Abraitis
Projektas