Founded in 1975 as an independent research institution, now part of Vilnius University, the Institute of Biotechnology strives to maintain the high standards of excellence in scientific endeavour, research training and technological advance with its main focus in a broadly defined field of molecular biotechnology including nucleic acid and protein technologies, bioinformatics, molecular diagnostics, drug design, next generation epigenomic and gene editing technologies. The Institute provides an interface between advanced education, basic research and technological development for the economic and social benefit of Lithuania.

 

Department of Bioinformatics

Spausdinti
Ceslovas Venclovas
Head of the Laboratory:
Dr. Česlovas Venclovas
Tel.: 8-5-269-1881
Fax.: 8-5-260-2116
E-mail: venclovas@ibt.lt
Bioinformatics lab
Staff:
Dr. Albertas Timinskas
Dr. Mindaugas Margelevičius
Rytis Dičiūnas
Project (MoBiLi) scientists:
Dr. Visvaldas Kairys
Dr. Ieva Mitašiūnaitė-Besson
Postdocs:
Dr. Justas Dapkūnas
Doctoral students:
Darius Kazlauskas
Kliment Olechnovič
Kęstutis Timinskas
Jolita Višinskienė
Students:
Algirdas Grybauskas
Nerijus Verseckas
Mantas Marcinkus

In Bioinformatics Laboratory we mainly deal with protein sequences and their three-dimensional structures. There are two main directions of our research:

  • Methods development. We aim at improving computational methods for sequence comparison and protein structure prediction (mainly in comparative modeling) as well as methods for assessment of protein structure quality.
  • Application of computational methods to biological problems. Most often we use computational methods to characterize structure and interactions of both individual proteins and their complexes. In these studies we tend to focus on proteins/protein complexes that function in DNA metabolism including DNA replication, recombination and repair. Our objective is to make inferences regarding structural and functional features, molecular mechanisms, interactions, etc. that can be tested experimentally. Most of such studies are joint collaborations with experimentalists.
Sources of financial support for our previous and current research:
  • Howard Hughes Medical Institute , International Research Scholars Program
  • Research Council of Lithuania
  • Ministry of Education and Science
  • EU Seventh Framework Programme (FP7)

  • Lab accomplishments

  • Software
  • Publications
  • Models