Founded in 1975 as the all Union Research Institute of Applied Enzimology, currently,  the Institute of Biotechnology is mainly involved in research and training in the fields of biotechnology and molecular biology, including research and development of recombinant biomedical proteins, genetic and molecular studies of restriction modification phenomenon, developing of viruses diagnostics, epigenetic study of small RNA, drug design and synthesis, bioinformatics.

Department of Bioinformatics

	Head of the Laboratory: Dr. Česlovas Venclovas Tel.: 8-5-269-1881 Fax.: 8-5-260-2116 E-mail: venclovas@ibt.lt
		Staff: Dr. Albertas Timinskas Dr. Mindaugas Margelevičius Rytis Dičiūnas Project (MoBiLi) scientists: Dr. Visvaldas Kairys Dr. Ieva Mitašiūnaitė-Besson Postdocs: Dr. Justas Dapkūnas Doctoral students: Darius Kazlauskas Kliment Olechnovič Kęstutis Timinskas Jolita Višinskienė Students: Algirdas Grybauskas Nerijus Verseckas Mantas Marcinkus

In Bioinformatics Laboratory we mainly deal with protein sequences and their three-dimensional structures. There are two main directions of our research:

• Methods development. We aim at improving computational methods for sequence comparison and protein structure prediction (mainly in comparative modeling) as well as methods for assessment of protein structure quality.
• Application of computational methods to biological problems. Most often we use computational methods to characterize structure and interactions of both individual proteins and their complexes. In these studies we tend to focus on proteins/protein complexes that function in DNA metabolism including DNA replication, recombination and repair. Our objective is to make inferences regarding structural and functional features, molecular mechanisms, interactions, etc. that can be tested experimentally. Most of such studies are joint collaborations with experimentalists.

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  • Department of Protein - DNA Interactions
  • Department of Biological DNA Modification
  • Department of Biothermodynamics and Drug Design
  • Department of Eukaryote Gene Engineering
  • Department of Immunology and Cell Biology

  • Department of Bioinformatics

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