1. Sasnauskas, G., Zakrys, L., Zaremba, M., Cosstick, R., Gaynor, J. W., Halford, S. E. & Siksnys, V., A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active site. Nucleic Acids Res, 2010, vol. 38, 2399-2410. (http://dx.doi.org/10.1093/nar/gkp1194, DOI: 10.1093/nar/gkp1194)
  2. Zaremba, M., Owsicka, A., Tamulaitis, G., Sasnauskas, G., Shlyakhtenko, L. S., Lushnikov, A. Y., Lyubchenko, Y. L., Laurens, N., van den Broek, B., Wuite, G. J. L. & Siksnys, V., DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme. Nucleic Acids Res, 2010. (http://dx.doi.org/10.1093/nar/gkq560, DOI: 10.1093/nar/gkq560)
  3. Zaremba, M. & Siksnys, V., Molecular scissors under light control. Proc Natl Acad Sci U S A, 2010, vol. 107, 1259-1260. (http://dx.doi.org/10.1073/pnas.0913923107, DOI: 10.1073/pnas.0913923107)
  4. Gilmore, J. L., Suzuki, Y., Tamulaitis, G., Siksnys, V., Takeyasu, K. & Lyubchenko, Y. L., Single-molecule dynamics of the DNA-EcoRII protein complexes revealed with high-speed atomic force microscopy. Biochemistry, 2009, vol. 48, 10492-10498. (http://dx.doi.org/10.1021/bi9010368, DOI: 10.1021/bi9010368)
  5. Golovenko, D., Manakova, E., Tamulaitiene, G., Grazulis, S. & Siksnys, V., Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII. Nucleic Acids Res, 2009, vol. 37, 6613-6624. (http://dx.doi.org/10.1093/nar/gkp699, DOI: 10.1093/nar/gkp699)
  6. Ibryashkina, E. M., Sasnauskas, G., Solonin, A. S., Zakharova, M. V. & Siksnys, V., Oligomeric structure diversity within the GIY-YIG nuclease family. J Mol Biol, 2009, vol. 387, 10-16. (http://dx.doi.org/10.1016/j.jmb.2009.01.048, DOI: 10.1016/j.jmb.2009.01.048)
  7. Neely, R. K., Tamulaitis, G., Chen, K., Kubala, M., Siksnys, V. & Jones, A. C., Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes. Nucleic Acids Res, 2009, vol. 37, 6859-6870. (http://dx.doi.org/10.1093/nar/gkp688, DOI: 10.1093/nar/gkp688)
  8. Gasiunas, G., Sasnauskas, G., Tamulaitis, G., Urbanke, C., Razaniene, D. & Siksnys, V., Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family. Nucleic Acids Res, 2008, vol. 36, 938-949. (http://dx.doi.org/10.1093/nar/gkm1090, DOI: 10.1093/nar/gkm1090)
  9. Sasnauskas, G., Connolly, B. A., Halford, S. E. & Siksnys, V., Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme. Nucleic Acids Res, 2008, vol. 36, 3969-3977. (http://dx.doi.org/10.1093/nar/gkn343, DOI: 10.1093/nar/gkn343)
  10. Sukackaite, R., Grazulis, S., Bochtler, M. & Siksnys, V., The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution. J Mol Biol, 2008, vol. 378, 1084-1093. (http://dx.doi.org/10.1016/j.jmb.2008.03.041, DOI: 10.1016/j.jmb.2008.03.041)
  11. Szczepanowski, R. H., Carpenter, M. A., Czapinska, H., Zaremba, M., Tamulaitis, G., Siksnys, V., Bhagwat, A. S. & Bochtler, M., Central base pair flipping and discrimination by PspGI. Nucleic Acids Res, 2008, vol. 36, 6109-6117. (http://dx.doi.org/10.1093/nar/gkn622, DOI: 10.1093/nar/gkn622)
  12. Tamulaitiene, G. & Siksnys, V., NotI is not boring. Structure, 2008, vol. 16, 497-498. (http://dx.doi.org/10.1016/j.str.2008.03.003, DOI: 10.1016/j.str.2008.03.003)
  13. Tamulaitis, G., Zaremba, M., Szczepanowski, R. H., Bochtler, M. & Siksnys, V., How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets. Nucleic Acids Res, 2008, vol. 36, 6101-6108. (http://dx.doi.org/10.1093/nar/gkn621, DOI: 10.1093/nar/gkn621)
  14. Kaus-Drobek, M., Czapinska, H., SokoĊ‚owska, M., Tamulaitis, G., Szczepanowski, R. H., Urbanke, C., Siksnys, V. & Bochtler, M., Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically. Nucleic Acids Res, 2007, vol. 35, 2035-2046. (http://dx.doi.org/10.1093/nar/gkm064, DOI: 10.1093/nar/gkm064)
  15. Sasnauskas, G., Connolly, B. A., Halford, S. E. & Siksnys, V., Site-specific DNA transesterification catalyzed by a restriction enzyme. Proc Natl Acad Sci U S A, 2007, vol. 104, 2115-2120. (http://dx.doi.org/10.1073/pnas.0608689104, DOI: 10.1073/pnas.0608689104)
  16. Shlyakhtenko, L. S., Gilmore, J., Portillo, A., Tamulaitis, G., Siksnys, V. & Lyubchenko, Y. L., Direct visualization of the EcoRII-DNA triple synaptic complex by atomic force microscopy. Biochemistry, 2007, vol. 46, 11128-11136. (http://dx.doi.org/10.1021/bi701123u, DOI: 10.1021/bi701123u)
  17. Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Siksnys, V. & Bochtler, M., Restriction endonucleases that resemble a component of the bacterial DNA repair machinery. Cell Mol Life Sci, 2007, vol. 64, 2351-2357. (http://dx.doi.org/10.1007/s00018-007-7124-9, DOI: 10.1007/s00018-007-7124-9)
  18. Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Szczepanowski, R. H., Urbanke, C., Siksnys, V. & Bochtler, M., Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA. J Mol Biol, 2007, vol. 369, 722-734. (http://dx.doi.org/10.1016/j.jmb.2007.03.018, DOI: 10.1016/j.jmb.2007.03.018)
  19. Sukackaite, R., Lagunavicius, A., Stankevicius, K., Urbanke, C., Venclovas, C. & Siksnys, V., Restriction endonuclease BpuJI specific for the 5'-CCCGT sequence is related to the archaeal Holliday junction resolvase family. Nucleic Acids Res, 2007, vol. 35, 2377-2389. (http://dx.doi.org/10.1093/nar/gkm164, DOI: 10.1093/nar/gkm164)
  20. Tamulaitis, G., Zaremba, M., Szczepanowski, R. H., Bochtler, M. & Siksnys, V., Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence. Nucleic Acids Res, 2007, vol. 35, 4792-4799. (http://dx.doi.org/10.1093/nar/gkm513, DOI: 10.1093/nar/gkm513)
  21. Bochtler, M., Szczepanowski, R. H., Tamulaitis, G., Grazulis, S., Czapinska, H., Manakova, E. & Siksnys, V., Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease. EMBO J, 2006, vol. 25, 2219-2229. (http://dx.doi.org/10.1038/sj.emboj.7601096, DOI: 10.1038/sj.emboj.7601096)
  22. Tamulaitiene, G., Jakubauskas, A., Urbanke, C., Huber, R., Grazulis, S. & Siksnys, V., The crystal structure of the rare-cutting restriction enzyme SdaI reveals unexpected domain architecture. Structure, 2006, vol. 14, 1389-1400. (http://dx.doi.org/10.1016/j.str.2006.07.002, DOI: 10.1016/j.str.2006.07.002)
  23. Tamulaitis, G., Sasnauskas, G., Mucke, M. & Siksnys, V., Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease. J Mol Biol, 2006, vol. 358, 406-419. (http://dx.doi.org/10.1016/j.jmb.2006.02.024, DOI: 10.1016/j.jmb.2006.02.024)
  24. Tamulaitis, G., Mucke, M. & Siksnys, V., Biochemical and mutational analysis of EcoRII functional domains reveals evolutionary links between restriction enzymes. FEBS Lett, 2006, vol. 580, 1665-1671. (http://dx.doi.org/10.1016/j.febslet.2006.02.010, DOI: 10.1016/j.febslet.2006.02.010)
  25. Zaremba, M., Sasnauskas, G., Urbanke, C. & Siksnys, V., Allosteric communication network in the tetrameric restriction endonuclease Bse634I. J Mol Biol, 2006, vol. 363, 800-812. (http://dx.doi.org/10.1016/j.jmb.2006.08.050, DOI: 10.1016/j.jmb.2006.08.050)
  26. Grazulis, S., Manakova, E., Roessle, M., Bochtler, M., Tamulaitiene, G., Huber, R. & Siksnys, V., Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. Proc Natl Acad Sci U S A, 2005, vol. 102, 15797-15802. (http://dx.doi.org/10.1073/pnas.0507949102, DOI: 10.1073/pnas.0507949102)
  27. Zaremba, M., Sasnauskas, G., Urbanke, C. & Siksnys, V., Conversion of the tetrameric restriction endonuclease Bse634I into a dimer: oligomeric structure-stability-function correlations. J Mol Biol, 2005, vol. 348, 459-478. (http://dx.doi.org/10.1016/j.jmb.2005.02.037, DOI: 10.1016/j.jmb.2005.02.037)